Reaction to a change: adapt to, adjust to, A big change: transform our lives, revolutionise, to bring about sweeping /radical/ major/ wholesale changes, A negative change: do harm to, cause damage to, have devastating effects on, have a deleterious effect on, have a detrimental effect on/ to the detriment of/be detrimental to (the future), A positive change: have a positive effect on, enable, facilitate, improve, Possible effects+ idioms: implications, consequences , face the music, grin and bear, come to terms with,

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