1) Which term refers to a local area of tissue damage produced by disease, injury, or surgery? a) Abscess b) Mutation c) Deformity d) Lesion 2) What is an animal’s primary means of keeping out most invading organisms? a) Blood and lymph b) Skin and mucous membranes c) Antibodies d) Hair or fur 3) Why is a treatment for external parasites applied in multiple administrations several days apart? a) To prevent new eggs from being laid b) To prevent causing a toxic reaction in the animal c) To kill newly hatched larvae d) To kill adults resistant to the initial treatment 4) What zoonotic disease may be transmitted by the body fluids of infected nonhuman primates? a) Measles b) B virus c) Toxoplasmosis d) Tuberculosis 5) When should husbandry for quarantined animals be scheduled? a) After completing work with the other animals in the facility b) At the beginning of the day c) Midday when work demands are less hectic d) Before animals not in quarantine have been checked 6) What is NOT a likely cause of neoplastic growth? a) Viral infection b) Chronic irritation c) Toxin d) Fungal infection 7) Both too much and too little of specific vitamins and minerals can result in which type of disease? a) Nutritional b) Hereditary c) Degenerative d) Metabolic 8) Infection with what human disease is potentially fatal to marmosets? a) B virus b) Herpes simplex c) Tuberculosis d) Salmonellosis 9) Which condition in frogs results from an infection or a metabolic disorder and can impair their equilibrium in water? a) Salmonellosis b) Red leg c) Fungal infection d) Bloat 10) Which type of cells break down pathogens that have been trapped in the lymph nodes? a) Macrophages b) Thrombocytes c) Granulocytes d) Lymphocytes 11) What is a first step for an animal technician to physically examine an animal? a) Examine the appearance of sentinel animals. b) Observe the animal before restraining it. c) Restrain the animal to examine it closely. d) Check the health records from the day before. 12) For which disease must personnel with access to NHPs be immunized or provide documentation of immunity? a) Herpes simplex virus b) Measles c) Tuberculosis d) B virus 13) Where should an animal be housed if the animal is suspected to have a disease? a) Isolation room b) Conventional animal room c) Loading dock d) Quarantine room 14) What is active immunity? a) The immune response to an attack by a foreign substance b) The inflammatory response c) The autoimmune response to a chronic infection d) The transfer of immunity from one animal to another 15) A newborn’s temporary immunity is known as _______ immunity. a) maternal b) passive c) vertical d) congenital 16) Which type of testing has been adopted by many facilities in place of sentinel testing? a) Pyrogen testing b) Toxicity testing c) Biological testing d) Molecular techniques 17) When invading pathogens spread throughout the body, which type of cells mount an inflammatory response to destroy them? a) Platelets b) Nerve cells c) White blood cells d) Red blood cells 18) Which is NOT a factor that determines the severity of a disease? a) Number of host cells involved b) Role of damaged tissues in body function c) Mode of transmission d) Extent of tissue damage 19) Which type of disease is defined as one in which the host has visible abnormalities associated with the disease? a) Acute b) Clinical c) Chronic d) Enzootic 20) What agent of infectious disease is described as a misfolded protein? a) Virus b) Fungi c) Bacteria d) Prion 21) What is the usual treatment of an abscess? a) Bandaging the area so that the animal will not chew on it b) Opening the abscess to drain the pus followed by rinsing with a disinfecting solution c) A disinfectant wash in the area of the abscess d) Antibiotics and a steroid shot 22) Which type of disease has a rapid onset and a short duration? a) Acute b) Subclinical c) Neoplastic d) Local 23) A surgical procedure to remove embryos from potentially infected dams and implant them in uninfected surrogate mothers is known as _______ . a) transgenesis b) cloning c) cryopreservation d) rederivation 24) A disease that continues in a subclinical state is said to be _______ a) degenerative b) benign c) acute d) latent 25) In which species is self-mutilation most commonly seen? a) Rats b) Nonhuman primates c) Swine d) Mice 26) Which would NOT be a cause of a congenital disease? a) Age-related changes in adults b) Health problem in a pregnant dam c) Mutation in an embryo d) Toxin exposure of a breeding male

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