Simone J. is a 40-year-old dental hygiene student who suffers from migraine headaches and clinical depression. She is currently taking paroxetine (Paxil) for the depression, oral contraceptives, and propranolol as needed for her migraines. She agrees to be a patient for her classmate, and when her vital signs are taken in the clinic, her blood pressure is 160/100 mm Hg, although it has always been in the normal range in the past. During questioning, she tells her clinician classmate that she recently switched types of oral contraceptives because of weight gain. She also reports that her mouth is dry.1) When reading the drug information handbook, the clinician discovers that elevated blood pressure can occur when one is taking this brand of oral contraceptive. What is the term for this type of drug reaction?, Allergic reaction, Toxic reaction, Drug interaction, Idiosyncratic reaction, Adverse drug reaction, Simone has not had a migraine headache since she switched oral contraceptives, but while she is in the dental chair, she has an aura and asks the clinician if she can take a propranolol. Shortly after taking the drug, she complains of dizziness and loses consciousness. Which of the following is the most likely cause of this reaction?, Adverse drug reaction, Drug interaction, Idiosyncratic reaction, Toxic reaction, Allergic reaction, Paxil is a U.S. Food and Drug Administration category B drug. If Simone becomes pregnant, can she safely continue taking her antidepressant?, Yes, No, The prevention of pregnancy by administration of oral contraceptives is termed the, teratogenic effect, hypersensitivity reaction, local effect, therapeutic effect, idiosyncratic effect, Simone reads in her dental hygiene textbook that dry mouth is a common condition in patients who take Paxil. Which term describes this condition?, Hypersensitivity reaction, Therapeutic effect, Adverse effect or side effect, Teratogenic effect, Idiosyncratic effect, Simone needs quadrant periodontal debridement due to heavy interproximal calculus deposits, and local anesthetic is indicated. After administration of a topical benzocaine anesthetic, her lips swell, and she develops hives all over her body. Which is the most likely type of hypersensitivity reaction she is experiencing?, Type I, Type IV, Type III, Type V, Type II, Drug allergies are an immunologic response resulting in a reaction such as a rash or anaphylaxis. Drug allergies are the most common type of adverse drug reactions., Both statements are false., The first statement is true; the second statement is false., The first statement is false; the second statement is true., Both statements are true., Paxil has a therapeutic index (TI) of 40. The significance of this therapeutic index is that Paxil is a(n), therapeutically useful drug, fairly toxic medication, nontherapeutically useful drug, fairly safe medication, a and c only, b and d only.

Simone Case study Chapter 4

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