Cystic fibrosis: Due to recessive allele, Need 2 copies of allele for disease, Thick mucus clogs lungs, Treat with physiotherapy, No cure, Shorter life expectancy, Parents can be symptomless carriers , 25 % chance of disease if parents are heterozygous, Both parents must pass on a disease allele, Polydactyly: Due to dominant allele, Need only 1 disease allele, Extra fingers/toes, Can treat with surgery, Parents cannot be symptomless carriers, 75% chance of disease if parents are heterozygous,

Polydactyly vs Cystic fibrosis

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