Bohr effect is the release of oxygen by haemoglobin molecules in response to high partial pressure of carbon dioxide. Explain briefly. Carbon dioxide interacts with ____ forming carbonic acid. Carbonic acid dissociates into ____ / HCO3- / hydrogen carbonate ion and H+. This causes blood plasma to become more ____/ more H+/ lower pH. Thus, haemoglobin ____ towards oxygen decrease. Causing Haemoglobin to release oxygen to ____ tissue. The oxygen dissociation curve will shift to the ____. Explain the relationship between pH and haemoglobin dissociation in very active tissues. In very active tissues, ____ from cellular respiration reacts with water to form ____, thus ____ the pH. Because ____ affect haemoglobin shape, a drop in pH shifts the oxygen dissociation curve toward the ____. Haemoglobin releases more ____ at a lower pH, supporting increased cellular respiration.

Bohr effect

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