Multiple sclerosis - Loss of colour vision , Motor Neurone Disease - Mixed upper and lower motor neurone signs, Subacute Cord Degeneration - Absent ankle reflexes and upgoing plantars , Guillain-Barre Syndrome - Distal lower limb muscle weakness, Miller-Fisher Syndrome - Opthalmoplegia, ataxia and hyporeflexia , Friedrich's ataxia - Ataxia, loss of proprioception and absent tendon reflexes in lower limbs, Huntington's chorea - Involuntary movement, cognitive impairment and loss of coordination , Parkinson's disease - Resting tremor, bradykinesia and rigidity, Peripheral Neuropathy - Glove and stocking distribution of sensory loss , Stroke - Contralateral UL/LL weakness, speech disturbance and visual inattention ,

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