take on new responsibilities, to accept new duties or tasks, fulfill a lifelong ambition, to achieve something you have wanted to do for many years, put down roots, to settle in a place and build a stable life there, face a major setback, to experience a serious problem that delays your progress, come of age, to reach adulthood or become more mature, work your way up, to gradually move to a higher position through hard work, embark on a new chapter, to begin a new and important period in your life, reach a milestone, to achieve an important stage or goal, start afresh, to start again in a new or different way, land your dream job, to successfully get the job you have always wanted, take the plunge, to finally decide to do something important or challenging, a turning point, a moment when an important change happens

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