1) What is the movement of a drug from where it is administered, through the blood to other tissues in the body known as? a) Medication blockage b) Medication distribution c) First pass effect d) Biodynamics 2) ADME is an acronym used in medication distribution. What does the A stand for? a) Adrenalin b) Asprin c) Administration d) Absorbance 3) ADME is an acronym used in medication distribution. What does the D stand for? a) Development b) Distribution c) Dopamine d) Distance 4) ADME is an acronym used in medication distribution. What does the M stand for? a) Medical b) Movement c) Metabolism d) Medication 5) ADME is an acronym used in medication distribution. What does the E stand for? a) Excretion b) Exit c) Extracellular fluid d) Extrapolate 6) Which of the following are possible anatomical barriers to drugs being distributed to cells/tissues? a) Blood - brain barrier b) Blood - liver barrier c) Blood - placenta barrier d) Blood - testis barrier e) Plasma proteins 7) True or false? Drugs travelling through the blood are not likely to be metabolised (broken down) a) True b) False 8) True or false? Drugs taken orally enter the lymphatic system first? a) True b) False 9) Distribution of drugs between compartments in the body is dependent on which of the following factors? Tick all that apply. a) Permeability of barriers b) Fat solubility of drugs c) Alcohol levels d) Bone density e) pH of compartments f) Binding capacity 10) True or false? Cytochrome P450 are enzymes which metabolise drugs? a) True b) False 11) True or false? Glucuronic acid is insoluble, which means it can't be excreted in the urine. a) True b) False 12) Aspirin is metabolised into salicylic acid. Salicylic acid is the active drug, which means aspirin is... a) Inactive b) A prodrug c) Excreted 13) Which of the following methods are used to excrete toxins   a) Sneezing b) Defecating c) Sweating d) Urinating e) Exhaling f) Vomiting 14) Excretion by filtering out the toxins involves which organ? a) Liver b) Stomach c) Kidneys d) Lungs 15) Drug dosage in patients with kidney damage needs to be carefully considered because the rate urine is being produced VU is... a) Happening too fast b) Happening too slow

Medication administration

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