Introduction, "Heartworm disease remains a major concern in canine health across tropical and subtropical regions.", "Previous studies have not sufficiently compared treatment protocols for advanced-stage infections.", "This study investigates the efficacy of a new antiparasitic drug in reducing microfilariae levels.", "Canine heartworm can lead to severe cardiopulmonary complications if left untreated.", "We hypothesize that earlier diagnosis leads to better treatment outcomes in infected dogs.", Methods, "A total of 30 dogs diagnosed with heartworm disease were included in the study.", "Subjects received a monthly oral dose of the test medication over a period of 12 weeks.", "Blood samples were collected on days 1, 14, 28, and 84 to monitor parasite levels.", "All animals were housed under identical conditions and observed daily for side effects.", "Ultrasound imaging was used to assess pulmonary artery changes before and after treatment.", Results, "After 12 weeks, 83% of the treated dogs showed a complete absence of microfilariae.", "No significant adverse effects were recorded in the treatment group.", "Parasite counts were reduced by an average of 76% in the first month of treatment.", "Statistical analysis revealed a p-value of less than 0.05, indicating significant improvement.", "Dogs treated with the standard protocol showed slower recovery compared to those on the experimental drug.", Discussion, "These findings support the effectiveness of the new drug in treating early-stage heartworm infections.", "The lack of adverse reactions suggests that the treatment is well-tolerated by canine subjects.", "One limitation of the study was the small sample size, which may affect generalizability.", "Future research should examine long-term outcomes and resistance development.", "This study contributes to the growing evidence that early intervention improves prognosis in heartworm-positive dogs."

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