Lidocaine (sodium channel blocker, class 1b), acute ventricular dysrhythmias, se: bradycardia, hypotension, dizziness, confusion, erythema at injection site, contraindications: advanced AV block, caution: hepatic disease, HF, interactions: other antiarrhythmic drugs, considerations: constant monitoring with an EKG, metoprolol (selective) propranolol (non selective), HTN, AMI, angina, HF, complications: bradycardia, hypotension. nonselective: bronchoconstriction, inhibition of glycogen breakdown in hypoglycemia, contraindications: bradycardia, heart block, asthma, bronchospasm. precautions: hypotension, DM, interactions: antihypetensives/digoxin can intensify hypotensive effects; insulin, considerations: do not stop abruptly, self-monitor HR daily, avoid OTC, african americans do not respond well to beta blockers alone for the control of HTN, Amiodarone (antiarrythmic, class III), life-threatening v tach and v fib, se: bradycardia, hypotension, hypo/hyper-thyroidism, hepatoxicity, photosensitivity, contraindications: pregnancy and breastfeeding, interactions: numerous drug interactions (depressants), grapefruit juice, considerations: indicated only for life-threatening arrhythmias because of risk for substantial toxicity, avpid excessive exposure to sunlight, Adenosine ( antiarrhythmic, class III), paroxysmal supraventricular tachycardia (PSVT), se: bradycardia, flushing, chest pain, and dyspnea (transient) bronchospasm, Contraindications: poison- or drug-related tachycardia, second- and third-degree heart block, and sick sinus syndrome; asthma, COPD, Considerations 1: short period of asystole may follow injection of adenosine (up to 15 seconds), half life is <5 seconds, considerations 2: Administer through port closest to Pt over 1 second followed by saline flush, immediately elevate the arm, Atropine (anticholinergics, muscarinic agonist), increase heart rate in bradycardia, pupil dilation, decrease salivary secretions pre-op, se: dry mouth, constipation, urinary retention, dilated pupils, blurred vision, tachycardia, urinary retention, interactions: anticholinergic drugs, considerations: IV onset immediate, peak action occurs in 5 minutes
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Antidysrhythmics 1
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