Aztecs - A warrior people who dominated the Valley of Mexico from 1100-1521, Cahokia - One of the largest urban centers created by the Mississippian peoples, containing 30,000 residents in 1250, Columbian Exchange - The transatlantic echange of plants, animals, and diseases that occured after the first European contact with the Americans, Treaty of Tordesillas - Negotiated by the pop in 1492 to resolve the territorial claims of Spain and the Protugese, Encomienda System - a license granted by the Spanish crown to royal officials to extract labor and tribute from native peoples in specified areas, Conquistador - a conqueror, especially one of the Spanish conquerors of Mexico and Peru in the 16th century, Pope - a determined and dynamic Pueblo leader who deeply resented the Spanish, Pueblo Revolt 1680 - Natives killed hundreds of Spaniards while destroying their buildings and burning their fields,

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