have a lot on your plate, have a great deal (or too much) to cope with, at the end of your rope, be exasperated and out of patience, at your wit's end, at the limits of your mental resources and don’t know how to proceed, a weight/load off your mind, being able to relieve yourself of some worry or stress, up to your neck in something, fully immersed in and occupied by something, at breaking point, the point at which a machine, organisation or system ceases to function because it is overworked or put under too much strain, take it out on someone, treating someone badly because you are feeling stressed about another situation, worried sick, extremely worried

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