Poikilocytosis - unusual variation in shape, Spherocytes - round, densely staining red cells that lack central pallor and have a smaller than normal diameter, Stomatocytes - the area of central pallor is elliptical rather than round, giving the cell the appearance of the opening of a mouth (stoma), Target cells (codocytes) - have a centrally located disk of hemoglobin surrounded by an area of pallor with an outer rim of hemoglobin adjacent to the cell membrane giving the cell the appearance of a target, Teardrop erythrocytes (dacryocytes) - red cells with one end round and the other end more pointed., Leptocytes (or wafer cells) - thin, flat cells with the hemoglobin at the periphery of the cell., Elliptocytes (ovalocytes) - range from slightly oval to elongated cigar-shaped forms., Sickle cells (drepanocytes) - elongated, sometimes crescent-shaped, erythrocytes with pointed ends, Acanthocytes (spur cells) - irregularly spaced blunted projections from the margin of the cells, Echinocytes (burr cells) - cells with cytoplasmic projections, but in contrast to acanthocytes, the projections are typically evenly spaced on the cell surface, more numerous (often 10 to 15), and frequently have sharper points, Schizocytes (schistocytes) - fragmented erythrocytes appearing in a variety of morphologic forms such as small triangular erythrocytes, helmet cells, and normal-size erythrocytes with 2 to 3 pointed surface projections (keratocytes, or "horn cells"), Bite cells (degmacytes) - Round erythrocytes with a single, elliptical or round surface defect, Rouleaux formation - stacking of erythrocytes, generally in a curving pattern.,
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Poikilocytes (irregularly shaped cells)
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Hematology
RBC Abnormalities
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