1) Glycogen is converted to monosaccharide units by: a) Glucokinase b) Glucose-6-phosphatase c) Glycogen phosphorylase d) Glycogen synthase 2) Which of the following enzymes acts in the pentose phosphate pathway? a) 6-phosphogluconate dehydrogenase b) Aldolase c) Glycogen phosphorylase d) Phosphofructokinase-1 3) The molecule generated in the pentose phosphate pathway is a) NADP b) ADP c) NADPH d) ATP 4) All of the following statements about the pentose phosphate pathway are true EXCEPT a) Its two functions are to produce NADPH and ribose-5-Phosphate b) It uses glucose-6-P as a substrate when producing NADPH and CO2 c) Glucose-6-phosphate dehydrogenase is the control enzyme and it is regulated by the NADPH concentration of the cell d) It is found in the mitochondria of liver, muscle and brain but is absent from most other tissues of the body 5) Which of the following is false about glycogen molecules? a) Glycogen is polysaccharide b) Glycogen is a polymer of beta-D-Glucose c) Glycogen consists of α(1-4) and α (1-6) glycosidic linkage d) Glycogen have are a helical structure with branching. 6) Liver glycogen contributes to the maintenance of glucose but not muscle glycogen. Which of the following enzyme isabsent in muscle? a) Glycogen phosphorylase b) Hexokinase c) Glucose-6-phosphatase d) Debranching enzyme 7) Which of the enzyme is responsible for the hydrolysis of α (1-6) glycosidic bond present at a branching point ofglycogen molecules? a) β-Glucosidase b) α- Glucosidase c) Glycosidase d) Phosphorylase 8) Which of the following metabolite allosterically activate glycogen phosphorylase? a) ATP b) AMP c) Glucose-6-phosphate d) Glucose-1-phosphate 9) Which of the following enzyme is responsible for the addition of UDP-Glucose to the existing chain? a) Glycogen synthase b) Glycogen polymerase c) Glycogen syntetase d) Glycogen lyase 10) The precursor to glycogen in the glycogen synthase reaction is a) Glucose-1-phosphate b) Glucose-6-phosphate c) UDP-Glucose d) UTP-Glucose. 11) Which of the following enzyme is used for the diagnosis of thiamine deficiency? a) Transketolase b) Glucose-6-Phosphate dehydrogenase c) Transaldolase d) Phosphogluconate e) dehydrogenase 12) Which of the following step is the rate-limiting step of the pentose phosphate pathway? a) Transketolase b) Glucose-6-Phosphate dehydrogenase c) Transaldolase d) Phosphogluconate dehydrogenase 13) A 46-year-old man presents for his annual physical. He states that he has been going to the bathroom more frequently than normal and has lost approximately 20 pounds (9.1 kg) in the past 6 months without trying. His random glucose today is 252mg/dL (14.0 mmol/L). Which of the following is most appropriate to confirm diagnosis of type 2 diabetes? a) A) Obtain a fasting glucose level in the morning. b) B) Have patient perform a 2-hour oral glucose tolerance test. c) C) Nothing; there is enough information available to diagnose patient with type 2 diabetes d) D) Obtain a repeat random glucose level 14) The oxidation of 3 mol of glucose by the pentose phosphate pathway may result in the production of a) 2 mol of pentose, 4 mol of NADPH and 8 mol of CO2 b) 3 mol of pentose, 4 mol of NADPH and 3 mol of CO2 c) 3 mol of pentose, 6 mol of NADPH and 3 mol of CO2 d) 4 mol of pentose, 6 mol of NADPH and 6 mol of CO2 15) Conversion of xylulose 5-phosphate to ribulose 5-phosphate is catalyzed by a) Phosphopentose epimerase b) Transaldolase c) Transketolase d) Phosphopentose isomerase

BBT3101 Tutorial 2

Tlač
Vložiť

Rebríček

Vizuálny štýl

Možnosti

Prepnúť šablónu

Obnoviť automaticky uložené: ?