1) Which hormone is secreted by the S cells of the duodenum in response to acidic chyme? a) Gastrin  b) Secretin  c) Cholecystokinin (CCK)  d) Somatostation 2) Which of the following is not true about immune system in GIT? a) GI immunocytes secrete many immunocytes b) Peyer’s patches are important components c) They are not involved in causation of inflammatory bowel disease d) GIT immunocytes constitute about 50% of total immunocytes in the body 3) Which hormone is considered a universal inhibitor, suppressing secretion of most other GI hormones? a) Gastrin b) Glucagon-like peptide 1 (GLP-1) c) Secretin d) Somatostatin 4) What is the approximate length of the Gastrointestinal Tract (GIT) from mouth to anus? a) 5 meters b) 10 meters c) 15 meters d) 20 meters 5) Which division of the autonomic nervous system is mainly excitatory to GIT motility and secretions? a) Sympathetic (T8-L2) b) Parasympathetic (vagus and sacral) c) Somatic d) Enteric only 6) The condition caused by congenital absence of ganglion cells in submucosal and myenteric plexuses is: a) Hirschsprung disease b) Zollinger-Ellison syndrome c) VIPoma d) Gastrocolic reflex 7) Which hormone is secreted by G cells and stimulates HCl secretion? a) Secretin b) Gastrin c) VIP d) Somatostatin 8) CCK (Cholecystokinin) primarily stimulates: a) Pancreatic enzyme secretion and gallbladder contraction b) Gastric acid stimulation c) Intestinal motility decrease d) Blood flow vasoconstriction 9) Which plexus of the enteric nervous system primarily controls gastrointestinal motility? a) Submucosal (Meissner’s) plexus  b) Myenteric (Auerbach’s) plexus  c) Celiac plexus  d) Hypogastric plexus 10) Which of the following is not a function of VIP? a) Increases intestinal secretions b) Causes vasoconstriction c) Causes relaxation of intestinal smooth muscles d) Inhibits gastric acid secretion 11) Which of the following statements is not true? a) Motilin increases GI motility b) Guanylin decreases chloride secretion into the intestine c) Somatostatin inhibits GI secretion d) Peptide YY inhibits gastric secretion and motility 12) Which of the following layer has Auerbach’s plexus? a) Serosa b) Lamina propria c) Muscular layer d) Muscularis mucosa 13) Which of the following is true for Ghrelin? a) Strong anorexigenic agent b) Secreted from small intestine c) Acts on arcuate nucleus of hypothalamus d) Inhibits secretion of growth hormone from anterior pituitary 14) Which of the following is false about reflexes in GIT? a) The long reflex is known as central reflex b) Chemoreceptors mediate local reflex c) Enterogastric reflex is an example of long reflex d) Local reflexes are mediated by enteric nervous system 15) A 45-year-old man presents with recurrent epigastric pain and watery diarrhea. Endoscopic evaluation reveals multiple peptic ulcers in the duodenum. Laboratory investigations show markedly elevated fasting serum gastrin levels. A pancreatic tumor is suspected. Which of the following physiological effects best explains the patient’s symptoms? a) Decreased bicarbonate secretion from pancreas  b) Increased gastric acid secretion due to stimulation of parietal cells  c) Reduced lower esophageal sphincter tone  d) Inhibition of gastric motility via enteric nervous system

Introduction to Digestive system

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