Substrates collides with the active site of enzymes and they bind together., Active site has a complimentary shape to the substrate., Enzyme catalyses the breakdown of the substrate into products., Substrate molecule., The fit between enzyme and substrate is like a lock and key. they are specific to one another., The enzyme molecule is unchanged after the reaction and can be reused over and over again., Products are released from the active site..

Lock And Key Hypothesis

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