Edward Jenner was an English ____ who, in 1796, developed the first successful ____ vaccine. He noticed that ____ who caught ____, a mild disease, did not get smallpox. Jenner tested his idea by giving a boy cowpox and later exposing him to smallpox, proving it provided protection. His work was ____ because it showed that disease could be ____, not just treated. Although vaccines were ____ at first, Jenner’s discovery laid the foundation for modern ____ and the eventual ____ of smallpox, marking a major turning point in medical history and public health.

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