Pain is an output of the brain, meaning that… - it is the brain’s interpretation of danger signals rather than a direct measure of tissue damage., The process of transduction begins when… - nociceptors detect a harmful stimulus such as heat, pressure, or chemicals., A-delta fibres are responsible for… - transmitting sharp, well-localised pain signals quickly due to their myelination., C-fibres carry signals that are… - slower and associated with dull, aching, or burning pain., These danger signals travel to the spinal cord via… - the dorsal root ganglion (DRG), which acts as a sorting centre for sensory input., In the spinal cord, pain signals can be modulated, meaning… - they may be amplified or inhibited depending on factors like touch input or prior sensitisation., According to the pain gate theory, activating A-beta fibres (e.g. through rubbing or TENS)… - can inhibit the transmission of pain signals by stimulating inhibitory interneurons., If the signal is strong enough, it is transmitted to the brain through… - ascending pathways such as the spinothalamic tract to the thalamus and cortex., The brain evaluates incoming signals alongside… - past experiences, emotional state, and contextual information before deciding to generate pain., The experience of pain is unique because… - it is shaped by both physiological inputs and psychological factors like memory, emotion, and belief.,

Match up - pain processing

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