Ibn Sina published Canon of Medicine listing 760 different drugs, Black Death arrives in England, William Harvey proves the circulation of the blood, Edward Jenner develops first vaccination against smallpox, James Simpson uses chloroform as an anaesthetic, Louis Pasteur publishes his Germ Theory, Joseph Lister uses carbolic acid as an antiseptic in surgery, First liberal social reforms, such as free school meals, introduced, Alexander Fleming discovers that penicillin kills bacteria, NHS comes into operation, First heart transplant is carried out.

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