action potential reaches synaptic knob , voltage-gated Ca2+ channels open in pre-synaptic membrane, Ca2+ enters pre-synaptic neurone, vesicles with acetylcholine move towards & fuse with pre-synaptic membrane , ACh released by exocytosis , ACh diffuses across synaptic cleft and..., ...binds to receptors on post-synaptic membrane , ligand-gated) Na+ channels open and Na+ enters post-synaptic neurone , depolarisation occurs, acetylcholinesterase breaks down and recycles ACh.

Harder - Cholinergic synapse function

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