Prokaryotes: No nucleus, small and simple, free floating DNA, Bacteria, Always single-celled organisms, Eukaryotes: Has a nucleus, large and complex, mitochondria, chloroplast, smooth ER, rough ER, golgi, lysosome, vacuole, Plants, Animals, Yeast, Can be single-celled organisms or an organism with many cells, Both: Has DNA, Has ribosomes, Has a cell membrane, Has cytoplasm, Can have a cell wall (not all do), Can have flagella (not all do),

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