In order to replicate the HIV virus binds to the protein CD4 which is most frequently found on T Helper cells., The capsid then fuses with the cell surface membrane and the RNA and reverse transcriptase enter the cell., The reverse transcriptase converts the RNA to DNA, which then moves into the nucleus of the cell., The HIV DNA causes the cell to make mRNA with instructions for making new viral proteins and RNA, The cells protein synthesis mechanisms use the mRNA to make HIV particles., Once made the HIV particles break away from the cell, taking a piece of its cell membrane to form the lipid envelope.

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