Step 1:, DNA gene is transcribed into an mRNA, Step 2:, mRNA leaves the nucleus via a nuclear pore, Step 3:, mRNA binds to a bound ribosome and is translated into the lumen of the RER, Step 4:, Inside the RER, the polypeptide is folded into its correct shape, Step 5:, The folded protein leaves the RER inside a vesicle and travels to the Golgi apparatus, Step 6:, The protein is packaged and sorted to its final destination, Step 7:, The protein travels by vesicle and a) it is secreted from the cell, OR b) it is taken to the lysosome OR c) it is inserted into the cell membrane

Endomembrane System

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