First contact with an antigen either as a vaccine or in the environment, Lymphocytes detect the specific antigen, Lymphocytes clone themselves to produce many plasma cells producing the specific antibody to destroy the antigen, Antibody level sufficient to destroy antigen, clone cells die off memory cells remain., Antigen encountered again, memory cells immediately recognise it and clone to produce specific antibody secreting cells., More antibodies produced faster, antigen destroyed before symptoms appear, person is immune..

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