CHEMO DRUGS - M C D, Methotrexate-CCS-CELL CYCLE SPECIFIC, Cisplatin- CCNS-CELL CYCLE NON-SPECIFIC, Doxorubicin- CYTOTOXIC ANTIBIOTIC, Considerations for chemo drugs: Handle meds carefully, using proper PPE, Cancer Chemotherapy SE/AR, Affect rapidly growing cells—normal and abnormal, Myelosuppression (bone marrow suppression) is a condition where bone marrow activity decreases, reducing the production of blood cells (white cells, red cells, platelets), Anemia loss of appetite (can give Dronabinol), GI disturbances, stomatitis, IV admin-extravasation: be careful; use of implanted ports—PICCs (upper arm, inferior vena cava), Risk for infection!! S/S of infection, bleeding gums, bruising, sore throat, etc, Alopecia, fatigue, infertility, Teaching with Chemo!, Encourage small, frequent meals (high in proteins and carbs) decreases n/v, Offer foods that may decrease nausea: cola, crackers, ginger ale, Increase fluids!, Advise pts to avoid visiting those with respiratory infections, Teach s/s of infection to seek HCP help, Avoid pregnancy for a few months after chemo drugs, Methotrexate -CELL CYCLE SPECIFIC- CCS, inhibits enzymes involved in nucleotide synthesis, which prevents cell division, hepatotoxicity, Mucositis / stomatitis!!, Cisplatin- CCNS, Antineoplastic, inhibition of DNA synthesis and cell growth, Use: treat advanced cancer of the bladder, ovaries, and TESTICLES, SE/AR: ototoxicity, HARD ON KIDNEYS, loss of appetite, hair loss, Monitor s/s of infection, usual chemo considerations and other blood dyscrasias, Ensure hydration, Doxorubicin, Use: advanced cancer of the bladder, ovaries, and THYROID, Route: IV (CAN CAUSE EXTRAVASATION), USE CENTRAL LINE, same considerations, but monitor for IV infiltration, Doxorubicin can cause dose-related cardiomyopathy. New dyspnea and reduced EF is concerning
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Chemotherapy
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