Inflammation Phase, begins immediately following injury, altered metabolism, redness, swelling, tenderness, increased tissue temperature, commonly 2-3 days, blood clot formation, migration of leukocytes, local vascular effects, disturbances of fluid exchange, vasoconstriction causing hypoxia, followed by vasodilation, hyperemia, debridement, Proliferation or Fibroplastic Phase, scar formation, first few hours up to 4-6 weeks, some tenderness to touch that gradually disappears, pain with particular movements that stress injured structure, rapid angiogenesis, growth of granulation tissue, increased oxygen delivery, breakdown of fibrin clot, fibroblast accumulation, collagen production, rapid increase in tensile strength of the wound, Remodeling or Maturation Phase, long-term process (up to several years), realignment of collagen fibres, wound contraction, conversion of Type III collagen to Type I, collagen cross-linking, reduction in capillaries, reduced swelling, reduction in fibroblasts

The Healing Process

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