Howell–Jolly bodies: purple spheres, usually about 0.5 μm in diameter, presenting singly, or rarely multiply, in the cytoplasm, remnants of DNA; they are ordinarily removed from red cells by the spleen, found in patients who have had splenectomies or are hyposplenic (e.g., sickle cell anemia) and rarely in megaloblastic anemias., inclusions of nuclear chromatin remnants, Heinz bodies: commonly seen in glucose-6-phosphate dehydrogenase, foci of denatured globin that interact with the erythrocyte membrane, inclusions of denatured hemoglobin caused by oxidative damage, Pappenheimer bodies: aggregates of ferritin, lysosomes, ribosomes, and degenerating mitochondria., inclusion bodies formed by phagosomes that have been engulfing excessive amounts of iron , Basophilic stippling: the stippled particles are aggregates of ribosomes, occurs in conditions in which the biosynthesis of hemoglobin is impaired, in a PBF, it is displayed by the small purplish dots (stippling) throughout their cytoplasm,

RBC inclusions - part 2

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