The Krebs cycle (sometimes called the ____) consists of a series of enzyme-controlled reactions 2 carbon (2C) Acetyl ____ enters the circular pathway from the link reaction in ____ Acetyl CoA formed from ____ (after the breakdown of lipids) and ____ enters directly into the Krebs Cycle from other metabolic pathways 4 carbon (4C) oxaloacetate accepts the ____ acetyl fragment from acetyl CoA to form the 6 carbon (6C) citrate Coenzyme A is released in this reaction to be reused in the next link reaction ____ is then converted back to oxaloacetate through a series of oxidation-reduction (redox) reactions The Krebs Cycle uses ____ from the ____ reaction and the regeneration of ____ to produce reduced NAD, reduced FAD and ATP Regeneration of oxaloacetate. Oxaloacetate is regenerated in the Krebs cycle through a series of redox reactions. Decarboxylation of citrate Releasing 2 ____ as waste gas. ____ (dehydrogenation) of citrate. Releasing H atoms that reduce ____ NAD and ____ These will be used during oxidative phosphorylation. 3 ____ and 1 FAD → 3NADH + H+ and 1 FADH2. Substrate linked phosphorylation, A phosphate is transferred from one of the intermediates to ____, forming 1 ATP to supply energy Because two acetyl-CoA molecules are produced from each glucose molecule, two cycles are required per glucose molecule. Therefore, at the end of two cycles, the products are: Two ____ Six ____ (reduced NAD) Two ____ (reduced FAD) Four ____

CAX KS5 The Krebs Cycle

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