1) What is the name of the first antibiotic developed? a) penicillin b) aspirin  c) digitalis  2) Which type of pathogen do antibiotics kill?  a) Bacteria b) Viruses 3) Which plant or microorganism did aspirin originate from? a) willow b) foxglove c) fungal mould 4) Which plant or microorganism did penicillin originate from? a) willow b) foxglove c) fungal mould 5) Why is it difficult to develop safe drugs to destroy viruses? a) Drugs that destroy viruses also damage body tissues b) There are too many viruses for the drugs to destroy c) Viruses are too small for the drugs to destroy 6) Which substance is used as an antibiotic? a) aspirin b) digitalis c) penicillin 7) Which antibiotic did not kill either type of bacteria? a) A b) B c) C d) D 8) Which antibiotic would be most effective to treat a person with a gonorrhea infection? a) A b) B c) C d) D 9) During pre-clinical testing in a laboratory, what is the drug not tested on?   a) cells/tissues b) healthy volunteers c) animals e.g. mice 10) During Phase 1 clinical trials, the drug is tested on healthy volunteers using low doses. What is the main purpose of Phase 1 testing?   a) To find the best dose to use b) To see if the drug is safe to use c) To see if the drug work 11) What is a placebo? a) Fake drug b) Anti-viral drug c) Antibiotic d) Painkiller 12) Who knows which patients are given the placebo and which patients are given the drug in a double blind trial? a) Not the patients or the doctors b) The patients and the doctors c) The patients but not the doctors  13) What three factors must doctors test a drug for in a trial? a) Appearance b) Toxicity c) Solubility d) Efficacy e) Taste  f) Dosage  14) For many years drugs have been extracted from plants. Which plant material was chewed as a painkiller? a) Blackcurrant berries  b) Foxglove leaves  c) Rose petals  d) Willow bark 15) Why must the results of drug trials be peer reviewed (checked by other scientists) before the drug is approved for use by the public? a) To increase public awareness of the new drug b) To speed up the approval process c) To prevent false claims 16) What term describes whether the drug works to treat the disease and make the person feel better? a) Efficacy b) Toxicity c) Dosage 17) What term describes whether the drug causes any side effects which makes the person ill? a) Efficacy b) Toxicity c) Dosage 18) What word describes the concentration of drug to be used and how often the drug should be given? a) Efficacy b) Toxicity c) Dosage 19) A drug has been tested on live animals. What is next stage in testing the drug?   a) Testing on cells in a laboratory b) Testing on healthy volunteers c) Testing on people with the disease 20) Which type of drug is described as a "cure"? a) Antibiotics b) Painkillers 21) Why cannot antibiotics be used to treat HIV infections? a) HIV is a virus b) HIV is a bacteria c) Antibotics do not kill viruses d) Antibiotics do not kill bacteria 

Testing Drugs

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