1) It is the change in DNA sequence due to copying mistakes during cell division a) Protein Synthesis b) Mutation c) Replication d) Translation 2) It is referred to as anything that causes a mutation. a) Error b) Hormones c) Mutagens d) Enzyme 3) It is a type of mutation that removes a base from a codon. a) Substitution b) Replication c) Deletion d) Insertion 4) ATG CCA AAT to ATG TCA AAT is an example of ____ mutation. a) Deletion b) Mutation c) Translation d) Substitution 5) A mutation that occurs during DNA replication. a) Gene mutation b) DNA mutation c) RNA mutation d) Protein mutation 6) What type of disease is caused by a protein hemoglobin defect? a) Cancer b) Sickle Cell Anemia c) Down Syndrome d) Cystic Fibrosis 7) Which of the following is true about mutations? a) They are never as simple as an incorrect codon in a DNA molecule b) They can be inherited if they are discovered in somatic cells. c) They can produce new alleles of existing genes. d) They occur before protein synthesis. 8) It is the cause of the most known human mutation. a) Radiation b) Inherited c) Viruses d) Spontaneous 9) All of the following can produce mutations, except for: a) Incest b) Radiation c) Microorganisms d) Chemicals 10) Which of these mutations will not alter the sequence of amino acids of a protein? a) Silent mutation b) Frameshift mutation c) Nonsense mutation d) Neutral mutation 11) When a point mutation in a gene replaces a single nucleotide, which of the following is NOT a possible outcome? a) Codon that codes for a “stop” codon b) Codon that codes for the same amino acid as the original sequence c) Codon that codes for a different amino acid d) Codon that cannot be transcribed into mRNA 12) What mutation has occurred here? T-G-A-C-C-A → T-G-A-G-C-A a) Deletion b) Insertion c) Substitution d) Nonsense 13) Genetic mutations can be... a) Beneficial, harmful, or neutral b) Beneficial only c) Harmful only d) Neutral only 14) Could an organism's offspring inherit a mutation found in a skin cell's DNA? a) Yes, since all genetic alterations are inherited by the offspring. b) Not. Only mutations that take place in the gametes, are transferred. c) Maybe. Only half of the body's genetic code is used by the cells. d) It would be hard to tell without knowing the species. 15) A ____ is a single nucleotide change in a gene sequence. a) Single error b) Point mutation c) Mono mutation d) Isolated mutation

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