1) Enzyme substrate complexes are formed because a) enzymes fit the substrate b) the active site and substrate are complementary and specific 2) Enzyme theory is described by a) lock and key b) induced fit 3) At low temperatures, rate of reaction is slow because a) enzymes and substrates have low KE b) enzymes denature 4) At high temperatures the enzyme denatures because a) the active site changes shape when the bonds in it are broken b) the substrate changes shape 5) Enzymes denature due to a) pH outside of the optimum and / or high temperatures b) high temperatures and / or high pH c)   6) Rate of reaction increases as substrate concentration increases until a) all substrates are broken down b) all active sites are filled 7) Increasing enzyme concentration will increase rate of reaction until a) substrate concentration becomes a limiting factor b) enzymes are used up 8) Enzymes are biological catalysts because a) they break down substrates b) they lower activation energy 9) When investigating the effect of temperature on rate of reaction, temperature is the a) dependent variable b) independent variable 10) When investigating the effect of substrate on rate of reaction, control variables will be a) substrate concentration b) pH and temperature

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